Deliberations about clinical pharmacogenetic testing in pediatric oncology.

IF 1.7 4区 医学 Q3 PHARMACOLOGY & PHARMACY
Personalized medicine Pub Date : 2021-07-01 Epub Date: 2021-05-11 DOI:10.2217/pme-2020-0120
Amalia M Issa, Sarah Ae Aboushawareb, David D Eisenstat, Greg Mt Guilcher, Geoffrey Liu, S Rod Rassekh, Caron Strahlendorf, Gesche Tallen, Reo Tanoshima, Bruce Carleton
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引用次数: 2

Abstract

This article summarizes the background, content and outcomes of a special meeting that was convened among oncologists and scientists to discuss the role of pharmacogenetic (PGx) testing in pediatric clinical oncology practice. This meeting provided an opportunity for what the lead author (AM Issa) refers to as the 'voice of the clinician' dynamic to be amplified in order to better understand how personalized or precision medicine applications such as PGx testing are adopted and incorporated into clinical settings and what we can learn from the experiences of current and ongoing implementation PGx approaches to further the implementation of precision medicine applications in real-world environments. Group dynamics and clinical experience with PGx testing and return of results shaped the discussion.

小儿肿瘤学临床药物遗传学检测的探讨。
本文总结了在肿瘤学家和科学家之间召开的讨论药物遗传学(PGx)测试在儿科临床肿瘤学实践中的作用的特别会议的背景、内容和结果。这次会议为第一作者(AM Issa)所说的“临床医生的声音”动态提供了一个机会,以便更好地了解个性化或精准医学应用(如PGx测试)如何被采用并纳入临床环境,以及我们可以从当前和正在实施的PGx方法的经验中学习到什么,以进一步在现实环境中实施精准医学应用。小组动态和临床经验的PGx测试和返回的结果形成了讨论。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Personalized medicine
Personalized medicine 医学-药学
CiteScore
3.30
自引率
4.30%
发文量
49
审稿时长
6-12 weeks
期刊介绍: Personalized Medicine (ISSN 1741-0541) translates recent genomic, genetic and proteomic advances into the clinical context. The journal provides an integrated forum for all players involved - academic and clinical researchers, pharmaceutical companies, regulatory authorities, healthcare management organizations, patient organizations and others in the healthcare community. Personalized Medicine assists these parties to shape thefuture of medicine by providing a platform for expert commentary and analysis. The journal addresses scientific, commercial and policy issues in the field of precision medicine and includes news and views, current awareness regarding new biomarkers, concise commentary and analysis, reports from the conference circuit and full review articles.
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