Three Consequent Pediatric Liver Transplant Deaths in the COVID-19 Era.

IF 0.3 Q4 TRANSPLANTATION
A Imam, C Karatas, R Imam, A Armutlu, N Mecit, A Karakaya, M Kalayoglu, T Kanmaz
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引用次数: 0

Abstract

The effect of COVID-19 on the transplant recipients is not well-established. Many reports underestimate the effect of COVID-19 on the immunosuppressed population. Herein, we report on 3 pediatric liver transplant recipients who were transplanted at our center between February 11 and March 10, 2020-during the COVID-19 pandemic era. The 3 patients aged between 5 and 10 months, had a rapid and aggressive respiratory deterioration that necessitated mechanical ventilation and extracorporeal life support; and eventually died. The clinical and pathological pictures likely represent COVID-19 pneumonia. Chest x-rays showed progressive infiltrates. Lung autopsies showed diffuse alveolar damage in two cases. We concluded that COVID-19 is very likely to have catastrophic effects on transplant recipients.

新冠肺炎时代三例儿童肝移植死亡
COVID-19对移植受者的影响尚未确定。许多报告低估了COVID-19对免疫抑制人群的影响。在此,我们报告了2020年2月11日至3月10日期间在我中心接受肝移植的3名儿童肝移植受者-在COVID-19大流行时期。3例患者年龄在5 ~ 10个月之间,呼吸系统迅速恶化,需要机械通气和体外生命支持;最后死了。临床和病理表现可能为COVID-19肺炎。胸部x光片显示进行性浸润。两例肺解剖显示弥漫性肺泡损伤。我们的结论是,COVID-19很可能对移植受者产生灾难性的影响。
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来源期刊
CiteScore
1.60
自引率
0.00%
发文量
0
审稿时长
12 weeks
期刊介绍: The International Journal of Organ Transplantation Medicine (IJOTM) is a quarterly peer-reviewed English-language journal that publishes high-quality basic sciences and clinical research on transplantation. The scope of the journal includes organ and tissue donation, procurement and preservation; surgical techniques, innovations, and novelties in all aspects of transplantation; genomics and immunobiology; immunosuppressive drugs and pharmacology relevant to transplantation; graft survival and prevention of graft dysfunction and failure; clinical trials and population analyses in the field of transplantation; transplant complications; cell and tissue transplantation; infection; post-transplant malignancies; sociological and ethical issues and xenotransplantation.
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