COVID-19-associated sleep disorders: A case report

Q2 Medicine

Neurobiology of Sleep and Circadian Rhythms Pub Date : 2020-11-01 DOI:10.1016/j.nbscr.2020.100057

Abeer A. Tony , Effat AE. Tony , Shazly B. Ali , Azza M. Ezzeldin , Amal A. Mahmoud

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引用次数: 26

Abstract

Purpose

We reported one patient infected with acute respiratory syndrome coronavirus-2 (SARS-CoV-2) presented with sleep disorders; insomnia and restless leg syndrome.

Methods

Patient data were obtained from medical records from Al-Raghy Isolation Hospital in Assuit University.

Results

A 49-year-old female patient presented with insomnia and restless leg syndrome associated with anosmia, ageusia. Three days before, she had developed a cough, malaise and athenia, headache, arthralgia, myalgia affecting mainly upper limbs, diarrhea and a fever followed by tachypnea. The naso-oropharyngeal swab test for coronavirus disease 2019 (COVID-19) by qualitative real-time reverse-transcriptase–polymerase-chain-reaction assay was positive. The patient was treated with Oseltamivir 75mg and clarithromycin 500 mg (12 hourly for each respectively) for 10 days with paracetamol. Two weeks later, the patient made a complete neurological and respiratory recovery.

Conclusion

Our case highlighted the rare occurrence of restless leg syndrome and insomnia during the COVID-19 pandemic. The era of sleep disorders spectrum in patients with COVID-19 remains to be characterized suggesting a frightening scientific association between COVID-19 and neuropsychiatric illness.

Abstract Image

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covid -19相关睡眠障碍:病例报告

目的报告1例急性呼吸综合征冠状病毒2型(SARS-CoV-2)感染患者出现睡眠障碍;失眠和不宁腿综合症。方法患者资料来源于Assuit大学Al-Raghy隔离医院的病历。结果1例女性患者，49岁，临床表现为失眠、不宁腿综合征并嗅觉丧失、老年。三天前，她出现咳嗽、乏力、头痛、关节痛、主要影响上肢的肌痛、腹泻和发烧，随后出现呼吸急促。定性实时逆转录-聚合酶链式反应法检测2019冠状病毒病(COVID-19)鼻咽拭子检测阳性。患者给予奥司他韦75mg，克拉霉素500mg(各12小时)，连用10天，同时给予扑热息痛。两周后，患者的神经系统和呼吸系统完全恢复。结论本病例突出了新冠肺炎大流行期间不宁腿综合征和失眠的罕见发生。COVID-19患者的睡眠障碍谱时代仍有待确定，这表明COVID-19与神经精神疾病之间存在可怕的科学关联。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Neurobiology of Sleep and Circadian Rhythms Neuroscience-Behavioral Neuroscience

CiteScore

4.50

自引率

0.00%

发文量

审稿时长

69 days

期刊介绍： Neurobiology of Sleep and Circadian Rhythms is a multidisciplinary journal for the publication of original research and review articles on basic and translational research into sleep and circadian rhythms. The journal focuses on topics covering the mechanisms of sleep/wake and circadian regulation from molecular to systems level, and on the functional consequences of sleep and circadian disruption. A key aim of the journal is the translation of basic research findings to understand and treat sleep and circadian disorders. Topics include, but are not limited to: Basic and translational research, Molecular mechanisms, Genetics and epigenetics, Inflammation and immunology, Memory and learning, Neurological and neurodegenerative diseases, Neuropsychopharmacology and neuroendocrinology, Behavioral sleep and circadian disorders, Shiftwork, Social jetlag.