The COVID-19 pandemic: is there a role for magnesium? Hypotheses and perspectives.

IF 1.5 4区医学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY

Magnesium research Pub Date : 2020-05-01 DOI:10.1684/mrh.2020.0465

Stefano Iotti, Federica Wolf, André Mazur, Jeanette A Maier

引用次数: 58

Abstract

More and more studies are accumulating about COVID-19. Some aspects of the pathogenesis of the disease recall events occurring in Mg deficiency, such as a drop of T cells, increased plasma concentration of inflammatory cytokines, and endothelial dysfunction. We hypothesize that a low Mg status, which is rather common, might foment the transition from mild to critical clinical manifestations of the disease. Epidemiological, clinical, and fundamental research is needed to clarify the potential role of Mg deficiency in COVID-19.

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2019冠状病毒病大流行:镁有作用吗?假设和观点。

关于COVID-19的研究越来越多。该疾病发病机制的某些方面回想起镁缺乏时发生的事件，如T细胞下降、血浆炎症细胞因子浓度升高和内皮功能障碍。我们假设，低镁状态，这是相当普遍的，可能会促进从轻微到严重的临床表现的转变。需要进行流行病学、临床和基础研究来阐明镁缺乏在COVID-19中的潜在作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Magnesium research 医学-内分泌学与代谢

CiteScore

3.50

自引率

9.40%

发文量

审稿时长

>12 weeks

期刊介绍： Magnesium Research, the official journal of the international Society for the Development of Research on Magnesium (SDRM), has been the benchmark journal on the use of magnesium in biomedicine for more than 30 years. This quarterly publication provides regular updates on multinational and multidisciplinary research into magnesium, bringing together original experimental and clinical articles, correspondence, Letters to the Editor, comments on latest news, general features, summaries of relevant articles from other journals, and reports and statements from national and international conferences and symposiums. Indexed in the leading medical databases, Magnesium Research is an essential journal for specialists and general practitioners, for basic and clinical researchers, for practising doctors and academics.