Colectomy and health-related Quality of Life in children with ulcerative colitis.

IF 2.6 4区医学 Q2 Medicine

Minerva pediatrica Pub Date : 2024-02-01 Epub Date: 2020-05-15 DOI:10.23736/S2724-5276.20.05750-3

Valeria Dipasquale, Maria A Catena, Lucia Paiano, Giuseppe Trimarchi, Carmelo Romeo, Giuseppe Navarra, Girolamo Mattioli, Claudio Romano

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引用次数: 0

Abstract

Background: Restorative proctocolectomy and ileal pouch-anal anastomosis (IPAA) is the recommended elective surgery for children with ulcerative colitis (UC). The aim of this study was to evaluate functional and long-term health-related Quality of Life (HRQoL) outcomes of surgery in pediatric patients with UC.

Methods: We reviewed the hospital records of all pediatric patients who had undergone surgery for UC between January 2009 and December 2016 in the Units of Pediatric Gastroenterology and Surgery, of both the University Hospital of Messina, and the Gaslini Children's Hospital of Genoa. Surgical treatment was represented by restorative proctocolectomy and laparoscopic IPAA. Patients and parents were interviewed by telephone before and after surgery and responded to the modified IMPACT III questionnaire about health outcomes and HRQoL. The questionnaire was scored on a five-point scale with higher scores indicating a better HRQoL. The total score ranged from 35 (worst HRQoL) to 175 (best HRQoL).

Results: Data were obtained in 30 patients (16 males), with a median age of 12 (range 3-16). The median amount of time elapsed after the operation was 3 years (range 1-4.5). Preoperative scores were very low in all 4 domains of the questionnaire. Postoperatively, HRQoL measures improved significantly (P<0.05) on symptoms, school attendance, social activities, and emotional aspects. Overall, nearly all were completely satisﬁed with the outcome of surgery.

Conclusions: Our data confirmed that surgical treatment improves the overall HRQoL in pediatric patients with UC.

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结肠切除术与溃疡性结肠炎患儿的健康相关生活质量。

背景：修复性直肠结肠切除术和回肠袋-肛门吻合术（IPAA）是溃疡性结肠炎（UC）患儿的推荐选择性手术。本研究旨在评估 UC 儿童患者手术的功能性和长期健康相关生活质量（HRQoL）结果：我们查阅了2009年1月至2016年12月期间在墨西拿大学医院和热那亚加斯利尼儿童医院小儿胃肠病学和外科接受手术治疗的所有儿科UC患者的住院记录。手术治疗以恢复性直肠切除术和腹腔镜IPAA为代表。患者和家长在手术前后均接受了电话访问，并回答了有关健康结果和心身健康生活质量的改良IMPACT III问卷。问卷采用五级评分法，分数越高，表示 HRQoL 越好。总分从 35 分（最差 HRQoL）到 175 分（最佳 HRQoL）不等：共获得 30 名患者（16 名男性）的数据，中位年龄为 12 岁（3-16 岁不等）。术后时间中位数为 3 年（1-4.5 年不等）。术前，问卷中所有 4 个方面的得分都很低。术后，患者的 HRQoL 指标明显改善（结论：我们的数据证实，手术治疗可改善患者的 HRQoL：我们的数据证实，手术治疗可改善 UC 儿童患者的整体 HRQoL。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Minerva pediatrica PEDIATRICS-

CiteScore

2.70

自引率

3.80%

发文量

审稿时长

>12 weeks

期刊介绍： Minerva Pediatrica publishes scientific papers on pediatrics, neonatology, adolescent medicine, child and adolescent psychiatry and pediatric surgery. Manuscripts may be submitted in the form of editorials, original articles, review articles, special articles, letters to the Editor and guidelines. The journal aims to provide its readers with papers of the highest quality and impact through a process of careful peer review and editorial work.