Metastatic intradural extramedullary spinal cord tumor from ovarian cancer: A case report with a literature review.

The Journal of Spinal Cord Medicine Pub Date : 2022-03-01 Epub Date: 2020-03-23 DOI:10.1080/10790268.2020.1739380
Yuki Tajima, Masahito Takahashi, Takuya Kawai, Makoto Higashi, Hideto Sano, Shoichi Ichimura, Hiroaki Kobayashi
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引用次数: 1

Abstract

Context: Metastatic intradural extramedullary spinal cord tumors are extremely rare.Findings: A 76-year-old woman presented with intractable neck pain. Three years earlier, she had been treated for ovarian cancer with bilateral salpingo-oophorectomy. A year later, she underwent resection of a brain metastasis. Magnetic resonance imaging (MRI) showed an encapsulated intradural extramedullary mass at C4-C5. C4-C5 hemilaminectomy, tumor resection, and biopsy were performed. Histological examination of the resection revealed an adenocarcinoma. After surgery, her intolerable neck-shoulder pain was fully resolved, and she had no difficulties with daily living activities. However, two months later, she underwent gamma knife radiosurgery for the recurrent metastatic brain tumor, and four months later, she died from cachexia.Conclusion: Although cases of metastatic intradural extramedullary spinal tumors from ovarian cancer are extremely rare, their possibility should be considered in the differential diagnosis. A history of brain metastases and enhancement on T1-weighted MRI were helpful for making an accurate diagnosis.

Abstract Image

卵巢癌转移性硬膜内髓外脊髓肿瘤1例并文献复习。
背景:转移性硬膜内髓外脊髓肿瘤极为罕见。结果:一名76岁女性以难治性颈部疼痛为主诉。三年前,她接受了双侧输卵管卵巢切除术的卵巢癌治疗。一年后,她接受了脑转移切除手术。MRI显示C4-C5处硬膜内髓外包覆肿块。行C4-C5半椎板切除术、肿瘤切除术和活检。切除的组织学检查显示为腺癌。手术后,她难以忍受的颈肩疼痛完全缓解,日常生活活动没有困难。然而,两个月后,她因复发性转移性脑瘤接受了伽玛刀放射手术,四个月后,她死于恶病质。结论:虽然卵巢癌转移性硬膜内髓外脊髓肿瘤极为罕见,但在鉴别诊断时应考虑其可能性。脑转移病史和t1加权MRI增强有助于准确诊断。
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