Early Lymph Node Metastasis May Predict Poor Prognosis in Soft Tissue Sarcoma.

IF 1.6 Q4 ONCOLOGY
International Journal of Surgical Oncology Pub Date : 2019-12-12 eCollection Date: 2019-01-01 DOI:10.1155/2019/6708474
Makoto Emori, Hiroyuki Tsuchie, Hiroyuki Nagasawa, Tomoko Sonoda, Arihiko Tsukamoto, Junya Shimizu, Yasutaka Murahashi, Emi Mizushima, Kohichi Takada, Kazuyuki Murase, Kotoe Iesato, Keita Igarashi, Tsukasa Hori, Masaki Yamamoto, Shintaro Sugita, Naohisa Miyakoshi, Tadashi Hasegawa, Yoichi Shimada, Toshihiko Yamashita
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引用次数: 9

Abstract

Background: Lymph node metastasis (LNM) is a relatively rare event in soft tissue sarcoma. An association between the timing of LNM detection and patient prognosis is presently unknown.

Patients and methods: We retrospectively analyzed the clinicopathological features of 33 patients with LNM between 2001 and 2015. Analysis of the timing of LNM diagnosis was grouped according to patients presenting LNM in either <8 months (the median time from primary tumor diagnosis to LNM) or ≥8 months after primary tumor diagnosis.

Results: A relationship between the primary tumor size and the timing of the LNM was not significantly found (Rs = 0.0088, p=0.96). Sixteen patients had an LNM detection duration of <8 months, and 17 patients had a duration of ≥8 months. The 5-year survival for patients with an LNM detection duration of <8 months and ≥8 months was 19% and 71%, respectively (p=0.0016). There were 19 patients with pulmonary metastases. Among them, there were 13 patients with a duration of primary tumor diagnosis to LNM of <8 months and 6 with a duration of ≥8 months (p=0.01).

Conclusion: Early LNM (<8 months) may predict poor prognosis in soft tissue sarcoma.

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软组织肉瘤早期淋巴结转移可能预示预后不良。
背景:在软组织肉瘤中,淋巴结转移(LNM)是一个相对罕见的事件。LNM检测时间与患者预后之间的关系目前尚不清楚。患者与方法:回顾性分析2001 - 2015年33例LNM患者的临床病理特征。结果:原发肿瘤大小与肿瘤发生时间无显著相关性(Rs = 0.0088, p=0.96)。16例患者的LNM检测时间(p=0.0016)。肺转移19例。其中13例患者从原发肿瘤诊断至LNM的时间(p=0.01)。结论:早期LNM (
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来源期刊
CiteScore
3.70
自引率
0.00%
发文量
5
审稿时长
20 weeks
期刊介绍: International Journal of Surgical Oncology is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies in all areas of surgical oncology.
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