{"title":"Thyroid Hormone and Alcoholic Fatty Liver: The Developmental Input.","authors":"Arturo Hernandez","doi":"10.1111/acer.14145","DOIUrl":null,"url":null,"abstract":"The liver is a main target of thyroid hormones (TH), which can regulate the expression of multiple genes in this tissue, most notably, those associated with the metabolism and physiology of lipids. Systemic TH status is associated with biochemical parameters dependent on liver function, including cholesterol level. For this reason, the liver is considered a desirable therapeutic target for tissue-specific thyromimetic action. This article is protected by copyright. All rights reserved.","PeriodicalId":7410,"journal":{"name":"Alcoholism, clinical and experimental research","volume":"43 9","pages":"1834-1837"},"PeriodicalIF":3.2000,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/acer.14145","citationCount":"3","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Alcoholism, clinical and experimental research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1111/acer.14145","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2019/7/24 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 3
Abstract
The liver is a main target of thyroid hormones (TH), which can regulate the expression of multiple genes in this tissue, most notably, those associated with the metabolism and physiology of lipids. Systemic TH status is associated with biochemical parameters dependent on liver function, including cholesterol level. For this reason, the liver is considered a desirable therapeutic target for tissue-specific thyromimetic action. This article is protected by copyright. All rights reserved.
期刊介绍:
Alcoholism: Clinical and Experimental Research''s scope spans animal and human clinical research, epidemiological, experimental, policy, and historical research relating to any aspect of alcohol abuse, dependence, or alcoholism. This journal uses a multi-disciplinary approach in its scope of alcoholism, its causes, clinical and animal effect, consequences, patterns, treatments and recovery, predictors and prevention.