Relapsing Kikuchi-Fujimoto Disease Requiring Prolonged Steroid Therapy.

Case Reports in Emergency Medicine Pub Date : 2019-03-07 eCollection Date: 2019-01-01 DOI:10.1155/2019/6405687
Ulrich Gerwig, Rolf Guenter Weidmann, Gregor Lindner
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引用次数: 3

Abstract

We report the case of a 26-year-old woman with an eight-week history of painfully enlarged cervical lymph nodes, recurrent headache, and malaise. Her medical history was unremarkable. The physical examination showed multiple enlarged cervical lymph nodes. Laboratory examination was unremarkable, and magnetic resonance tomographic imaging showed multiple enlarged cervical lymph nodes with aspect of a lymphoma. Lymph node biopsy revealed Kikuchi-Fujimoto disease, histologically characterized by histiocytic necrotizing lymphadenitis. A therapeutic trial with nonsteroidal anti-inflammatory drugs (NSAID) showed no effect, so steroid therapy was started. Due to relapse of symptoms after steroid withdrawal the tapering regimen was prolonged for a total of seven months.

Abstract Image

Abstract Image

复发的菊chi- fujimoto病需要长期类固醇治疗。
我们报告一个26岁的女性病例,有8周的颈部淋巴结肿大的痛苦史,复发性头痛和不适。她的病史一般。体格检查显示颈部多发肿大淋巴结。实验室检查无明显异常,核磁共振断层成像显示多发性颈部肿大淋巴结伴淋巴瘤征。淋巴结活检显示菊池-藤本病,组织学特征为组织细胞坏死性淋巴结炎。一项使用非甾体抗炎药(NSAID)的治疗试验显示没有效果,因此开始使用类固醇治疗。由于类固醇停药后症状复发,减量治疗方案延长了7个月。
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