{"title":"Meniere's Disease.","authors":"William P R Gibson","doi":"10.1159/000490274","DOIUrl":null,"url":null,"abstract":"<p><p>This article reviews 3 aspects of Meniere's disease (MD), which have been recently revisited: namely, the pathologic mechanism causing the attacks of vertigo, the clinical diagnosis, and the medical and surgical treatments. The characteristic attacks of vertigo are unlikely to be due to membrane ruptures, so a hypothesis that the vertigo is caused by a volume of endolymph shifting suddenly from the cochlea into the pars superior is suggested. The definite diagnosis according to the American Academy of Otolaryngology HNS 1995 criteria [<citeref rid=\"ref13\">13</citeref>] failed to exclude vestibular migraine sufficiently and a revision in 2015 [<citeref rid=\"ref14\">14</citeref>] has partly addressed this problem but another method which stresses the interaction of the cochlear and vestibular symptoms is described. The treatment of MD has been updated, providing evidence for each popular therapy. Newer treatments using intratympanic medications including steroid solutions and gentamicin are discussed. Finally, the role of cochlear implants is mentioned.</p>","PeriodicalId":39848,"journal":{"name":"Advances in Oto-Rhino-Laryngology","volume":"82 ","pages":"77-86"},"PeriodicalIF":0.0000,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000490274","citationCount":"9","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advances in Oto-Rhino-Laryngology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1159/000490274","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2019/1/15 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 9
Abstract
This article reviews 3 aspects of Meniere's disease (MD), which have been recently revisited: namely, the pathologic mechanism causing the attacks of vertigo, the clinical diagnosis, and the medical and surgical treatments. The characteristic attacks of vertigo are unlikely to be due to membrane ruptures, so a hypothesis that the vertigo is caused by a volume of endolymph shifting suddenly from the cochlea into the pars superior is suggested. The definite diagnosis according to the American Academy of Otolaryngology HNS 1995 criteria [13] failed to exclude vestibular migraine sufficiently and a revision in 2015 [14] has partly addressed this problem but another method which stresses the interaction of the cochlear and vestibular symptoms is described. The treatment of MD has been updated, providing evidence for each popular therapy. Newer treatments using intratympanic medications including steroid solutions and gentamicin are discussed. Finally, the role of cochlear implants is mentioned.
期刊介绍：
Material for each volume in this series has been skillfully selected to document the most active areas of otorhinolaryngology and related specialties, such as neuro-otology and oncology. The series reproduces results from basic research and clinical studies pertaining to the pathophysiology, diagnosis, clinical symptoms, course, prognosis and therapy of a variety of ear, nose and throat disorders. The numerous papers correlating basic research findings and clinical applications are of immense value to all specialists engaged in the ongoing efforts to improve management of these disorders. Acting as a voice for its field, the series has also been instrumental in developing subspecialities into established specialities.
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