Synchronous primary adenocarcinoma of the lung and pancreas: a case series and review of the literature.

Pub Date : 2017-07-01 Epub Date: 2017-07-14 DOI:10.2217/lmt-2017-0003
Akshjot Puri, Ly Ma, Gary V Walker, John Chang, Ron Z Shinar, Madappa N Kundranda
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引用次数: 4

Abstract

Aim: The frequency of pancreatic cancer in association with cancer of other organs ranges from 1 to 20%, with the most common ones being gastric, colon, thyroid and genitourinary. The presence of synchronous lung and pancreatic cancers is extremely rare.

Case series: Two patients with extensive smoking history and variable presentations were found to have simultaneous lung and pancreatic masses both lesions being different histologically and on immunohistochemical staining. After individualized treatment plans, the first patient remains free of disease and the second patient is being treated with a palliative intent.

Conclusion: The early recognition and treatment is important as there exists a significant survival difference in patients who have synchronous primaries as opposed to those with metastatic pancreatic adenocarcinoma.

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肺和胰腺的同步原发性腺癌:一个病例系列和文献回顾。
目的:胰腺癌合并其他脏器癌的发生率为1% ~ 20%,最常见的是胃癌、结肠癌、甲状腺癌和泌尿生殖系统癌。同时出现肺癌和胰腺癌是非常罕见的。病例系列:两例患者有广泛的吸烟史和不同的表现,发现同时有肺和胰腺肿块,两种病变在组织学和免疫组织化学染色上都不同。在个体化治疗计划之后,第一位患者仍然没有疾病,第二位患者正在接受姑息治疗。结论:与转移性胰腺腺癌相比,同步原发性胰腺腺癌患者的生存期存在显著差异,早期识别和治疗至关重要。
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