[Frequency and nature of drug related problems with corticosteroids in Belgian community pharmacies].

Journal de pharmacie de Belgique Pub Date : 2016-09-01
M Lelubre, M Koubaity, I De Wulf, K Boussery, G R Y De Meyer, V Foulon, V Lacour, S Steurbaut, T Van Hees, K Amighi, O Bugnon, C De Vriese
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Abstract

Aim Aims are: 1] Identify causes of Drug Related Problems (DRPs), interventions performed by pharmacists and results of corticosteroid- related problems and 2] distinguish between problems related to inhaled and general corticosteroids. Methods During 5 days of their internship, 534 final year students of pharmaceutical sciences in six Belgian universities collected DRPs encountered in community pharmacies, as well as related interventions performed by pharmacists and the result of the intervention. The DRPs' electronic registration was done through an adapted tool for Belgium based on the classification of Pharmaceutical Care Network Europe [PCNE- v 6.2]. Findings The frequency of DRPs is 24,8%. 766 DRPs (4,8%) related to corticosteroids, of which 351 were inhaled corticosteroids. The most common causes of corticosteroid-related problems (53- 59%) were technical causes. The most represented category of clinical causes was the inappropriate choice of drug [33-41%]. Pharmacists' intervention was similar for inhaled and general corticosteroids. Pharmacists intervened orally with patients in 38-40% of total interventions, and in writing in 16% of interventions. Pharmacists did not react in 16% of corticosteroid-related problems. 81-83% of PLMS were resolved partially or completely. Conclusion In conclusion, DRPs detected in community pharmacies related to corticosteroid are infrequent (4,8% of DRPs) but 82% of detected problems have been resolved. Furthermore, the study shows the importance for the Belgian health system to introduce an official DRPs classification and software facilitating their documentation in community pharmacies.

[比利时社区药房皮质类固醇药物相关问题的频率和性质]。
目的:1]确定药物相关问题(DRPs)的原因,药剂师实施的干预措施和皮质类固醇相关问题的结果;2]区分吸入性和一般性皮质类固醇相关问题。方法对比利时6所大学的534名药学专业大四学生进行为期5天的实习,收集他们在社区药房遇到的drp,以及药师的相关干预措施和干预结果。DRPs的电子注册是通过比利时基于欧洲药品护理网络[PCNE- v 6.2]分类的改编工具完成的。发现DRPs发生率为24.8%。766例drp(4.8%)与糖皮质激素相关,其中351例为吸入性糖皮质激素。皮质类固醇相关问题最常见的原因是技术原因(53- 59%)。最具代表性的临床原因是药物选择不当[33-41%]。药师对吸入和普通皮质类固醇的干预相似。药师对患者进行口头干预的比例为38-40%,书面干预的比例为16%。药剂师对16%的皮质类固醇相关问题没有反应。81 ~ 83%的PLMS得到部分或完全解决。结论在社区药房检测到与皮质类固醇相关的drp并不多见(占drp的4.8%),但82%的问题已得到解决。此外,该研究表明比利时卫生系统引入官方DRPs分类和软件的重要性,以促进社区药房的记录。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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