The Cretan Aging Cohort: Cohort Description and Burden of Dementia and Mild Cognitive Impairment.

IF 2.7 4区医学 Q2 CLINICAL NEUROLOGY

American Journal of Alzheimers Disease and Other Dementias Pub Date : 2019-02-01 Epub Date: 2018-09-27 DOI:10.1177/1533317518802414

Ioannis V Zaganas, Panagiotis Simos, Maria Basta, Stefania Kapetanaki, Symeon Panagiotakis, Irini Koutentaki, Nikolaos Fountoulakis, Antonios Bertsias, George Duijker, Chariklia Tziraki, Nikolaos Scarmeas, Andreas Plaitakis, Dimitrios Boumpas, Christos Lionis, Alexandros N Vgontzas

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引用次数: 0

Abstract

Our aim was to explore the burden of dementia in the Cretan Aging Cohort, comprised of 3140 persons aged ≥60 years (56.8% women, 5.8 ± 3.3 years formal education, 86.2% living in rural areas) who attended selected primary health-care facilities on the island of Crete, Greece. In the first study phase, a formal diagnosis of dementia had been reached in 4.0% of the participants. However, when selected 505 participants underwent thorough neuropsychiatric evaluation in the second phase of this study (344 with Mini-Mental State Examination [MMSE] <24 and 161 with MMSE ≥24), and results were extrapolated to the entire cohort, the prevalence of dementia and mild cognitive impairment was estimated at 10.8% (9.7%-11.9%) and 32.4% (30.8%-34.0%), respectively. Using both the field diagnostic data and the extrapolated data, the highest dementia prevalence (27.2%) was found in the 80- to 84-year-old group, who also showed the lowest educational level, apparently due to lack of schooling during World War II.

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克里特老龄队列：队列描述与痴呆症和轻度认知障碍的负担》（The Cretan Aging Cohort: Cohort Description and Burden of Dementia and Mild Cognic Impairment）。

我们的目的是研究克里特岛老年群组中痴呆症的负担，该群组由 3140 名年龄≥60 岁的人组成（56.8% 为女性，5.8 ± 3.3 年正规教育，86.2% 居住在农村地区），他们都曾在希腊克里特岛的选定初级医疗机构就诊。在第一阶段研究中，有 4.0% 的参与者被正式诊断为痴呆症。然而，在本研究的第二阶段，当选定的 505 名参与者接受了全面的神经精神病学评估（344 人接受了小型精神状态检查（Mini-Mental State Examination [MMSE]））后，他们被诊断为痴呆症。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

American Journal of Alzheimers Disease and Other Dementias GERIATRICS & GERONTOLOGY-CLINICAL NEUROLOGY

CiteScore

5.40

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： American Journal of Alzheimer''s Disease and other Dementias® (AJADD) is for professionals on the frontlines of Alzheimer''s care, dementia, and clinical depression--especially physicians, nurses, psychiatrists, administrators, and other healthcare specialists who manage patients with dementias and their families. This journal is a member of the Committee on Publication Ethics (COPE).