Reduced Lexical Access to Verbs in Individuals With Subjective Cognitive Decline.

IF 2.7 4区 医学 Q2 CLINICAL NEUROLOGY
Joël Macoir, Anne Lafay, Carol Hudon
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引用次数: 0

Abstract

The detection of cognitive impairment in individuals with subjective cognitive decline (SCD) may improve detection of the emergence of Alzheimer's disease (AD) pathology. This detection is challenging, however, given the lack of sensitive assessment tools. The main objective of this study was to determine the potential contribution of word production tasks to the detection of cognitive impairment in SCD. The performances of 20 individuals with SCD, healthy controls (HCs), and individuals with mild cognitive impairment (MCI) were compared on object and action naming and free fluency tasks. Participants with SCD performed similarly to HCs, while both groups differed significantly from participants with MCI in object naming and object fluency. Results showed that participants with SCD were at the midpoint between HCs and participants with MCI in action naming. They also revealed a HCs > SCD = MCI pattern in action fluency. This study provides evidence that verb production is impaired in SCD and that SCD is a pre-MCI condition.

主观认知能力下降的人对动词的词性获取能力降低。
检测主观认知功能减退(SCD)患者的认知功能障碍可提高对阿尔茨海默病(AD)病理变化的检测能力。然而,由于缺乏敏感的评估工具,这种检测具有挑战性。本研究的主要目的是确定造词任务对检测 SCD 认知功能障碍的潜在贡献。研究人员比较了 20 名 SCD 患者、健康对照组(HCs)和轻度认知障碍(MCI)患者在物体和动作命名以及自由流畅性任务中的表现。SCD 患者的表现与健康对照组相似,而在物体命名和物体流畅性方面,两组患者都与 MCI 患者有显著差异。结果显示,在动作命名方面,SCD 患者的表现介于 HCs 和 MCI 患者之间。在动作流畅性方面,他们也显示出 HCs > SCD = MCI 的模式。本研究提供的证据表明,SCD患者的动词产生能力受到了损害,而且SCD是一种MCI前状态。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
American Journal of Alzheimers Disease and Other Dementias
American Journal of Alzheimers Disease and Other Dementias GERIATRICS & GERONTOLOGY-CLINICAL NEUROLOGY
CiteScore
5.40
自引率
0.00%
发文量
30
审稿时长
6-12 weeks
期刊介绍: American Journal of Alzheimer''s Disease and other Dementias® (AJADD) is for professionals on the frontlines of Alzheimer''s care, dementia, and clinical depression--especially physicians, nurses, psychiatrists, administrators, and other healthcare specialists who manage patients with dementias and their families. This journal is a member of the Committee on Publication Ethics (COPE).
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