Case Report: First Coinfection Report of Mixed Leishmania infantum/Leishmania major and Human Immunodeficiency Virus-Acquired Immune Deficiency Syndrome: Report of a Case of Disseminated Cutaneous Leishmaniasis in Iran.
IF 1.9 4区 医学Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Alireza Badirzadeh, Mehdi Mohebali, Sadaf Sabzevari, Majid Ghafoori, Kourosh Arzamani, Mohammad Seyyedin, Seyed Ahmad Hashemi
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引用次数: 0
Abstract
Visceral leishmaniasis, a neglected tropical disease, is the third most common opportunistic disease in immunosuppressed patients, such as those affected by the human immunodeficiency virus (HIV)/acquired immune deficiency syndrome. Although the reports have been characterized as Leishmania/HIV coinfections, the occurrence of a mixed infection by two Leishmania species in HIV-positive patients is rare. Here, we present an atypical case of disseminated cutaneous leishmaniasis (DCL) in a 26-year-old HIV-positive man. The diagnosis of DCL was established using skin biopsy and histopathology examinations and confirmed by molecular techniques. This is the first case of a Leishmania/HIV coinfection due to a mixed infection of Leishmania infantum/Leishmania major in Iran.
内脏利什曼病是一种被忽视的热带疾病，是免疫抑制患者（如人类免疫缺陷病毒（HIV）/获得性免疫缺陷综合征患者）最常见的第三大机会性疾病。虽然这些报告被定性为利什曼原虫/HIV 合并感染，但在 HIV 阳性患者中出现两种利什曼原虫混合感染的情况并不多见。在此，我们介绍了一名 26 岁 HIV 阳性男性的播散性皮肤利什曼病（DCL）非典型病例。通过皮肤活检和组织病理学检查确定了 DCL 的诊断，并通过分子技术进行了确诊。这是伊朗首例因婴儿利什曼病/大利什曼病混合感染而引起的利什曼病/艾滋病毒合并感染病例。
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The American Journal of Tropical Medicine and Hygiene, established in 1921, is published monthly by the American Society of Tropical Medicine and Hygiene. It is among the top-ranked tropical medicine journals in the world publishing original scientific articles and the latest science covering new research with an emphasis on population, clinical and laboratory science and the application of technology in the fields of tropical medicine, parasitology, immunology, infectious diseases, epidemiology, basic and molecular biology, virology and international medicine.
The Journal publishes unsolicited peer-reviewed manuscripts, review articles, short reports, images in Clinical Tropical Medicine, case studies, reports on the efficacy of new drugs and methods of treatment, prevention and control methodologies,new testing methods and equipment, book reports and Letters to the Editor. Topics range from applied epidemiology in such relevant areas as AIDS to the molecular biology of vaccine development.
The Journal is of interest to epidemiologists, parasitologists, virologists, clinicians, entomologists and public health officials who are concerned with health issues of the tropics, developing nations and emerging infectious diseases. Major granting institutions including philanthropic and governmental institutions active in the public health field, and medical and scientific libraries throughout the world purchase the Journal.
Two or more supplements to the Journal on topics of special interest are published annually. These supplements represent comprehensive and multidisciplinary discussions of issues of concern to tropical disease specialists and health issues of developing countries
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