Why is Diagnosing MDD Challenging?

上海精神医学 Pub Date : 2016-12-25 DOI:10.11919/j.issn.1002-0829.216073

Xiaohua Liu, Kaida Jiang

引用次数: 5

Abstract

Depression is highly prevalent and one of the major contributors to disability worldwide. However, one of the findings from the DSM-5 field trials was that inter-rater reliability for diagnosing major depressive disorder was very poor. Why is diagnosing MDD so challenging? This article attempts to explain why undefined pathogenesis and complicated phenotypes complicate the diagnosis of MDD. However, further biomarker and translational research is still necessary to help clinicians screen and diagnose depression in the future rather than relying solely on current subjective diagnostic criteria.

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为什么诊断重度抑郁症具有挑战性?

抑郁症在世界范围内非常普遍，是造成残疾的主要原因之一。然而，DSM-5现场试验的一个发现是，诊断重度抑郁症的评分者之间的可靠性非常差。为什么诊断重度抑郁症如此具有挑战性?本文试图解释为什么不明确的发病机制和复杂的表型使MDD的诊断复杂化。然而，进一步的生物标志物和转化研究仍然是必要的，以帮助临床医生在未来筛选和诊断抑郁症，而不是仅仅依靠目前的主观诊断标准。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

上海精神医学

自引率

0.00%

发文量

2341

期刊介绍： Shanghai archives of psychiatry (bimonthly) was founded in 1959 and is sponsored by Shanghai Mental Health Center. The journal is aimed at mental health workers across the country, including psychiatrists and nurses, clinical psychologists, social workers, and people who are committed to the cause of mental health. It focuses on reporting clinical research results and practical experience in the field of psychiatry, and introduces the latest knowledge in psychiatry and related fields. The columns include monographs, case reports, clinical case discussions, reviews, mental health and law, and debates and discussions.