[Long-term Outcomes in Eyes Receiving of Bevacizumab Early in the Course of Branch Retinal Vein Occlusion].

Abstract

Purpose: To evaluate the effects of intravitreal bevacizumab (IVB) injections early in the course of branch retinal vein occlusion (BRVO).

Patients and methods: We conducted a retrospective review of 30 patients (30 eyes) with macular edema (ME) secondary to BRVO. The mean duration from the onset to the first IVB injection was 5 weeks. The mean observation period was 30 months. All patients were followed monthly, with administration of additional IVB injections if there was persistent or recurrent ME within 6 months after the first injection. The main outcome parameter was best-corrected visual acuity (BCVA) at 12 and 24 months. Rescue therapy including laser photocoagulation was done as needed.

Result: Mean BCVA improved significantly from logMAR 0.59 ± 0.24 at baseline to 0.04 ± 0.15 (p < 0.001)at 12 month, 0.06 ± 0.19(p < 0.001)at 24 month.

Conclusion: IVB injections given shortly after onset of branch retinal vein occlusion may result in a significant increase in vision in some patients.