Cuff-Free Blood Pressure Estimation Using Pulse Transit Time and Heart Rate.

Ruiping Wang, Wenyan Jia, Zhi-Hong Mao, Robert J Sclabassi, Mingui Sun
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引用次数: 91

Abstract

It has been reported that the pulse transit time (PTT), the interval between the peak of the R-wave in electrocardiogram (ECG) and the fingertip photoplethysmogram (PPG), is related to arterial stiffness, and can be used to estimate the systolic blood pressure (SBP) and diastolic blood pressure (DBP). This phenomenon has been used as the basis to design portable systems for continuously cuff-less blood pressure measurement, benefiting numerous people with heart conditions. However, the PTT-based blood pressure estimation may not be sufficiently accurate because the regulation of blood pressure within the human body is a complex, multivariate physiological process. Considering the negative feedback mechanism in the blood pressure control, we introduce the heart rate (HR) and the blood pressure estimate in the previous step to obtain the current estimate. We validate this method using a clinical database. Our results show that the PTT, HR and previous estimate reduce the estimated error significantly when compared to the conventional PTT estimation approach (p<0.05).

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利用脉搏传递时间和心率估算无袖带血压。
据报道,脉搏传递时间(PTT),即心电图(ECG)中r波峰值与指尖光容积描记图(PPG)之间的间隔,与动脉僵硬度有关,可用于估计收缩压(SBP)和舒张压(DBP)。这一现象已被用作设计便携式连续无袖带血压测量系统的基础,使许多心脏病患者受益。然而,基于ptt的血压估计可能不够准确,因为人体内的血压调节是一个复杂的、多元的生理过程。考虑到血压控制中的负反馈机制,我们在上一步中引入心率(HR)和血压估计值来获得当前估计值。我们使用临床数据库验证该方法。我们的研究结果表明,与传统的PTT估计方法相比,PTT、HR和先前的估计显著降低了估计误差(p
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