Adherence to dietary prescriptions in patients with acute food protein-induced enterocolitis syndrome.

IF 1.9 4区 医学 Q2 PEDIATRICS
Pediatric Investigation Pub Date : 2022-06-10 eCollection Date: 2022-09-01 DOI:10.1002/ped4.12333
Stefano Miceli Sopo, Dario Sinatti, Giorgio Sodero, Mariannita Gelsomino, Francesco Mastellone
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Abstract

Food protein-induced enterocolitis syndrome (FPIES) is a non-Immunoglobulin (non-IgE)-mediated food allergy. The elimination diet is the only therapy, the culprit food will be reintroduced if tolerance is acquired. However, it is possible that patients do not follow the recommendations given by the healthcare professional. We investigated if our advice to avoid the trigger food in patients with active FPIES and to reintroduce it in the diet in patients who achieved tolerance had been implemented. We interviewed by telephone the parents of children who were diagnosed with acute FPIES. About 23.2% of our patients disregarded our dietary recommendations: 6/42 (14.3%) of patients who passed a tolerance oral food challenge (OFC) did not eat the trigger food, 4/22 (18.2%) of patients who failed OFC ate the trigger food, and 9/18 (50.0%) of patients who did not perform a tolerance OFC ate the trigger food. We have analyzed some possible influencing factors and no difference was found to be statistically significant. Our results are in line with those reported for IgE-mediated food allergies. As has already been proposed by others, we suggest reassessing food consumption in all patients after a food challenge.

Abstract Image

急性食物蛋白诱发小肠结肠炎综合征患者遵守饮食处方的情况。
食物蛋白诱发小肠结肠炎综合征(FPIES)是一种非免疫球蛋白(非 IgE)介导的食物过敏。消除性饮食是唯一的治疗方法,如果获得耐受性,就会重新引入致病食物。然而,患者有可能不遵从医护人员的建议。我们调查了活动性 FPIES 患者是否执行了我们的建议,即避免食用诱发食物,并在患者产生耐受性后在饮食中重新添加诱发食物。我们通过电话采访了被确诊为急性 FPIES 患儿的家长。约有 23.2% 的患者无视我们的饮食建议:在通过耐受性口服食物挑战(OFC)的患者中,6/42(14.3%)的患者没有食用诱发食物;在OFC失败的患者中,4/22(18.2%)的患者食用了诱发食物;在未通过耐受性口服食物挑战的患者中,9/18(50.0%)的患者食用了诱发食物。我们对一些可能的影响因素进行了分析,结果发现两者之间的差异没有统计学意义。我们的研究结果与 IgE 介导的食物过敏的研究结果一致。正如其他人已经提出的建议,我们建议在食物挑战后重新评估所有患者的进食情况。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Pediatric Investigation
Pediatric Investigation Medicine-Pediatrics, Perinatology and Child Health
CiteScore
3.30
自引率
0.00%
发文量
176
审稿时长
12 weeks
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