Association of immune status with recurrent anal condylomata in human immunodeficiency virus-positive patients.

Journal of the Korean Society of Coloproctology Pub Date : 2012-12-01 Epub Date: 2012-12-31 DOI:10.3393/jksc.2012.28.6.294

Ji Hyun Sung, Eun Jung Ahn, Heung-Kwon Oh, Sei Hyeog Park

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引用次数: 8

Abstract

Purpose: An anal condyloma is a proliferative disease of the genital epithelium caused by the human papillomavirus. This condition is most commonly seen in male homosexuals and is frequently recurrent. Some reports have suggested that immunosuppression is a risk factor for recurrence of a condyloma. Thus, we investigated the risk factors for a recurrent anal condyloma in human immunodeficiency virus (HIV)-positive patients.

Methods: We retrospectively analyzed 85 consecutive patients who were diagnosed with and underwent surgery for an anal condyloma from January 2007 to December 2011. Outcomes were analyzed based clinical and immunologic data.

Results: Recurrent anal condylomata were found in 25 patients (29.4%). Ten cases (40.0%) were within postoperative 3 months. At postoperative 6 months, the CD4 lymphocyte count in the recurrent group was lower than it was in the nonrecurrent group (P = 0.023).

Conclusion: CD4-mediated immunosuppression is a risk factor for recurrent anal condylomata in HIV-positive patients.

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免疫状态与人类免疫缺陷病毒阳性患者复发性肛湿疣的关系。

目的:肛门尖锐湿疣是一种由人乳头瘤病毒引起的生殖上皮增生性疾病。这种情况最常见于男同性恋者，并且经常复发。一些报告表明免疫抑制是尖锐湿疣复发的危险因素。因此，我们调查了人类免疫缺陷病毒(HIV)阳性患者复发性肛门尖锐湿疣的危险因素。方法:回顾性分析2007年1月至2011年12月确诊并手术治疗肛门尖锐湿疣的85例患者。根据临床和免疫学数据分析结果。结果:复发性肛湿疣25例(29.4%)。术后3个月内10例(40.0%)。术后6个月，复发组CD4淋巴细胞计数低于非复发组(P = 0.023)。结论:cd4介导的免疫抑制是hiv阳性患者肛湿疣复发的危险因素。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Journal of the Korean Society of Coloproctology

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