Rivastigmine in the treatment of hypersexuality in Alzheimer disease.

Marco Canevelli, Giuseppina Talarico, Giuseppe Tosto, Fernanda Troili, Gian Luigi Lenzi, Giuseppe Bruno
{"title":"Rivastigmine in the treatment of hypersexuality in Alzheimer disease.","authors":"Marco Canevelli,&nbsp;Giuseppina Talarico,&nbsp;Giuseppe Tosto,&nbsp;Fernanda Troili,&nbsp;Gian Luigi Lenzi,&nbsp;Giuseppe Bruno","doi":"10.1097/WAD.0b013e31825c85ae","DOIUrl":null,"url":null,"abstract":"<p><p>Inappropriate sexual behaviors (ISB) represent uncommon and often misdiagnosed clinical disorders among patients with Alzheimer disease. So far, no randomized clinical trials regarding the treatment of ISB in demented people have been conducted, but available data from case series and isolated case reports suggest the efficacy of selective serotonin reuptake inhibitors (SSRIs), antipsychotics, antiandrogens, and H2-receptor antagonists. Controversial data exist on the therapeutic influence of cholinesterase inhibitors on sexual disorders. In the present article, we describe the case of an Alzheimer disease patient presenting hypersexuality, successfully treated with rivastigmine. Thus, we perform a revision of the existing literature regarding the therapeutical effect of cholinesterase inhibitors in the treatment of ISB. </p>","PeriodicalId":520551,"journal":{"name":"Alzheimer disease and associated disorders","volume":" ","pages":"287-8"},"PeriodicalIF":0.0000,"publicationDate":"2013-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/WAD.0b013e31825c85ae","citationCount":"16","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Alzheimer disease and associated disorders","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/WAD.0b013e31825c85ae","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 16

Abstract

Inappropriate sexual behaviors (ISB) represent uncommon and often misdiagnosed clinical disorders among patients with Alzheimer disease. So far, no randomized clinical trials regarding the treatment of ISB in demented people have been conducted, but available data from case series and isolated case reports suggest the efficacy of selective serotonin reuptake inhibitors (SSRIs), antipsychotics, antiandrogens, and H2-receptor antagonists. Controversial data exist on the therapeutic influence of cholinesterase inhibitors on sexual disorders. In the present article, we describe the case of an Alzheimer disease patient presenting hypersexuality, successfully treated with rivastigmine. Thus, we perform a revision of the existing literature regarding the therapeutical effect of cholinesterase inhibitors in the treatment of ISB.

利瓦斯汀治疗阿尔茨海默病中的性欲亢进。
不适当的性行为(ISB)是阿尔茨海默病患者中罕见且常被误诊的临床疾病。到目前为止,还没有关于痴呆患者的ISB治疗的随机临床试验,但从病例系列和孤立病例报告中获得的数据表明,选择性5 -羟色胺再摄取抑制剂(SSRIs)、抗精神病药物、抗雄激素和h2受体拮抗剂的疗效。关于胆碱酯酶抑制剂对性功能障碍的治疗作用存在争议。在本文中,我们描述的情况下,阿尔茨海默病患者表现出性欲亢进,成功地用利瓦斯汀治疗。因此,我们对有关胆碱酯酶抑制剂治疗ISB的疗效的现有文献进行了修订。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信