[Determination of total PSA rate and Gleason score during prostatic cancer in Urologic Hospital Center].

Dakar medical Pub Date : 2008-01-01
B Diao, P A Fall, B Fall, L Niang, Y Diallo, Y Sow, A Sarr, A Odzébé, A K Ndoye, M Bâ, B A Diagne
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引用次数: 0

Abstract

Aim: To dress biologic and histopathologic aspects of the prostatic cancer in urologic hospital center about a set of digital transrectal guided biopsies.

Methodology: It is a prospective study realized between January 2002 and March 2002 (26 months) studying patients with positive prostatic biopsy.

Results: Seventy two cases of prostatic cancer were noticed. Mean age of these patients was 69,9 years (54-91 years). Mean rate Total PSA was 134,8 ng/ml (6-2500 ng/ml). Repartition according Gleason score has revealed that only 35% of tumors were well differentiated. The study of correlation between Total PSA rate and Gleason grade has revealed that up to 10 ng/ml Total PSA rate, only 33% of patients had a Gleason grade between 2 and 4 (well differentiated tumor).

Conclusion: Actual biologic and histopathologic profile of prostatic cancer lays emphasis on later management.

泌尿外科医院中心前列腺癌患者总PSA率和Gleason评分的测定
目的:探讨一套经直肠指导活检对泌尿外科中心前列腺癌的生物学和组织病理学意义。方法:这是一项前瞻性研究,于2002年1月至2002年3月(26个月)对前列腺活检阳性患者进行研究。结果:共发现前列腺癌72例。患者平均年龄为69,9岁(54-91岁)。平均PSA为134,8 ng/ml (6-2500 ng/ml)。根据Gleason评分重新划分显示只有35%的肿瘤分化良好。总PSA率与Gleason分级的相关性研究显示,当总PSA率达到10 ng/ml时,只有33%的患者Gleason分级为2 - 4级(高分化肿瘤)。结论:前列腺癌的生物学和组织病理学特点强调晚期治疗。
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