[Evaluation of serological tests of toxoplasmosis in pregnant women realized at the Laboratory of Parasitology and Mycology of Le Dantec Teaching Hospital in 2002].

Abstract

Introduction: the toxoplasmosis can occur complications during pregnancy as serious repercussions on the foetus with the risks linked to this pathology such as abortion. However these complications can be avoided during the pregnancy by an early diagnosis. The objective of this study is to determine the prevalence of toxoplasmosis during pregnancy.

Materials and methods: we undertook this study on 109 pregnant women addressed to the laboratory of parasitology and mycology of the CHU Dantec for toxoplasmosis serological test on 2002. We used a immunoenzymatic technical in solid phase whose principle rests on the change of coloration in the presence of antibody of IgM or IgG; coloration whose intensity is function of the title of antibody. For that, two serological tests (S1 and S2), starting from two venous blood at 3 weeks of interval, are carried out among these pregnant women. This second serology will make it possible to confirm or cancel an evolutionary toxoplasmosis based on the variation of the title in antibody between the first (S1) and the second serology (S2). A control is carried out among these women among whom the diagnosis of the evolutionary toxoplasmosis was established.

Results: they show that with the first (S1), from the 109 patients, 3% were positive with the antibodies IgM type, 22% positive with IgG, and 11% positive with IgG and IgM. 36% of the women present a positive diagnostic at the first serology (S1). The second serology (S2) shows that among the 36% of the women diagnosed positive with the first serology, 11% made an evolutionary toxoplasmosis.

Conclusion: This study shows a rather significant of serological toxoplasmosis discovered fortuitously among pregnant women at the time of their assessment of pregnancy.