[Management of exocrin pancreatic tumor. About 129 cases].

Dakar medical Pub Date : 2008-01-01
B Fall, M Cissé, J M Ndoye, I Konaté
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Abstract

Management of exocrine pancreatic tumors is very difficult: Their impact is in upsurge and their diagnosis is very often made to an advanced stage that only allows the therapeutic palliative. To value the management of these tumors to the surgical clinic of Aristide Le Dantec hospital, authors achieved a retrospective survey on 8years (October 1994 to October 2002). Hundred twenty nine (129) cases of exocrine pancreatic tumors had been counted. It was about 71 men and 58 women of middle age of 56, 96 years. The length of middle evolution of the illness was of 8 months. The most frequent sign was jaundice, recovered at 80.9% of patients. Followed the thinning (79%), the pain (69%), the digestive stenosis (35%). Ultrasonography, scanner and x-ray of lungs permitted to make the diagnosis and the balance of extension. A laparoscopy had been made at 13 patients. A clinic and radiological classification had been used to distribute the tumors in 3 stages. At 46 patients in III stage, a therapeutic abstention had been decided. Patients to the II stage (n=77) had benefitted a palliative surgical treatment. It was about 74 biliary and digestive shunt and 3 alcoholic splanchnicectomy. The 6 patient to the I stage had benefitted a surgical resection. The middle hospitalization length was of 10.75 days. The rate of morbidity was 45.78%. Mortality was 29%. The median survival was of 3.6 months. The palliative surgical treatment had again indications facing these obstructive and locally advanced tumors. But the salute will come from the precocious diagnosis of these tumors to hope for a curative gesture.

胰腺外分泌激素肿瘤的治疗。约129例]。
外分泌胰腺肿瘤的治疗是非常困难的:它们的影响正在上升,它们的诊断往往是晚期,只允许姑息治疗。为了对阿里斯蒂德·勒·丹塔克医院外科诊所对这些肿瘤的处理进行评价,作者进行了8年(1994年10月至2002年10月)的回顾性调查。统计了129例外分泌胰腺肿瘤。大约有71名男性和58名女性年龄在56到96岁之间。中期病程为8个月。最常见的体征为黄疸,恢复率为80.9%。其次是变薄(79%),疼痛(69%),消化系统狭窄(35%)。超声、扫描及x线检查均可诊断及平衡伸展。对13例患者进行了腹腔镜检查。临床及影像学分型将肿瘤分为3期。在46例III期患者中,已决定放弃治疗。II期患者(n=77)受益于姑息性手术治疗。其中胆道和消化道分流术74例,酒精性内脏切除术3例。6例I期患者已行手术切除。中间住院时间为10.75 d。发病率为45.78%。死亡率为29%。中位生存期为3.6个月。姑息性手术治疗再次针对这些梗阻性和局部晚期肿瘤。但是,对这些肿瘤的过早诊断将带来对治愈的希望。
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