Development and application of a simplified clean-up procedure for the determination of polychlorinated biphenyls (PCBs) and polybrominated diphenyl ethers (PBDEs) in horse fat by gas chromatography-tandem mass spectrometry (GC-MS/MS).
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引用次数: 4
Abstract
A simplified clean-up procedure was developed in combination with gas chromatography-tandem mass spectrometry (GC-MS/MS) for the determination of polychlorinated biphenyls (PCBs) and polybrominated diphenyl ethers (PBDEs) in adipose tissue. Clean-up was performed by the successive application of a Mega Bond Elut silica column and a Bond Elut PCB column. Validation of the method was conducted according to European Union Commission Decision 2002/657/EC. In order to evaluate the applicability of the method, 44 horse fat samples were analysed. The total PCB concentration (sum of PCBs 28, 52, 101, 118, 138, 153 and 180) ranged from 5.35 to 140 ng g(-1) lipid weight. The total PBDE concentration (sum of BDEs 28, 47, 99, 100, 153, 154 and 183) ranged from below the decision limit to 6.34 ng g(-1) lipid weight.
采用气相色谱-串联质谱联用技术(GC-MS/MS)建立了脂肪组织中多氯联苯(PCBs)和多溴联苯醚(PBDEs)的简易净化方法。通过连续应用Mega Bond Elut硅胶柱和Bond Elut PCB柱进行清理。根据欧盟委员会决议2002/657/EC对该方法进行了验证。为了评价该方法的适用性，对44份马脂肪样品进行了分析。总PCB浓度(PCB 28、52、101、118、138、153和180的总和)范围为5.35 ~ 140 ng g(-1)脂质质量。总多溴二苯醚浓度(28、47、99、100、153、154和183的总和)范围从低于决定限值到6.34 ng g(-1)脂质重量。
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