{"title":"Neuronal loss in FIV-MD infected cats.","authors":"W R Buck, M Podell","doi":"10.1300/J128v02n01_05","DOIUrl":null,"url":null,"abstract":"<p><p>Previously, this laboratory has shown that the Maryland strain of feline immunodeficiency virus (FIV-MD) causes neurological disease in cats similar to human immunodeficiency virus type 1 (HIV-1) in people. Using morphometrical methods on neocortical histologic sections we now show a significant loss of neurons in FIV-MD infected cats compared to age-matched uninfected controls. The neuronal populations affected resembles those lost in HIV-1 infection of the brain in published reports, providing further evidence for the utility of FIV-MD infection as a model for HIV-1 infections of the brain.</p>","PeriodicalId":73854,"journal":{"name":"Journal of neuro-AIDS","volume":"2 1","pages":"69-77"},"PeriodicalIF":0.0000,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"6","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of neuro-AIDS","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1300/J128v02n01_05","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 6
Abstract
Previously, this laboratory has shown that the Maryland strain of feline immunodeficiency virus (FIV-MD) causes neurological disease in cats similar to human immunodeficiency virus type 1 (HIV-1) in people. Using morphometrical methods on neocortical histologic sections we now show a significant loss of neurons in FIV-MD infected cats compared to age-matched uninfected controls. The neuronal populations affected resembles those lost in HIV-1 infection of the brain in published reports, providing further evidence for the utility of FIV-MD infection as a model for HIV-1 infections of the brain.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
