Humoral and cellular immunity in children with Mycoplasma pneumoniae infection: a 1-year prospective study.

Iwona Stelmach, Malgorzata Podsiadłowicz-Borzecka, Tomasz Grzelewski, Pawel Majak, Wlodzimierz Stelmach, Joanna Jerzyńska, Marta Popławska, Jaroslaw Dziadek
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引用次数: 19

Abstract

To determine whether children have persistent abnormalities in cellular and humoral immunity development after acute Mycoplasma pneumoniae infection, serum immunoglobulin G (IgG), IgA, IgM, and IgE levels and lymphocyte phenotypes were determined. There were no changes in the levels of IgG, IgM, IgA, or CD4+ or CD19+ lymphocytes that were measured in M. pneumoniae-positive patients after 3 months or after 12 months, but there were increases in these in M. pneumoniae-negative patients. Serum IgE increased in M. pneumoniae-positive patients. We have shown alterations in immunity development after M. pneumoniae infection.

肺炎支原体感染儿童体液和细胞免疫:一项为期1年的前瞻性研究
为了确定急性肺炎支原体感染后儿童的细胞和体液免疫发育是否持续异常,我们检测了血清免疫球蛋白G (IgG)、IgA、IgM和IgE水平以及淋巴细胞表型。3个月或12个月后,肺炎支原体阳性患者的IgG、IgM、IgA、CD4+或CD19+淋巴细胞水平没有变化,但肺炎支原体阴性患者的这些水平有所增加。肺炎支原体阳性患者血清IgE升高。我们已经显示肺炎支原体感染后免疫发育的改变。
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