Role of optical coherence tomography angiography in Vogt-Koyanagi-Harada disease.

GMS ophthalmology cases Pub Date : 2021-03-12 eCollection Date: 2021-01-01 DOI:10.3205/oc000179
Stefano Erba, Andrea Govetto, Antonio Scialdone, Giuseppe Casalino
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引用次数: 4

Abstract

Vogt-Koyanagi-Harada disease (VKH) is an autoimmune severe multisystem condition characterized by both ocular and systemic findings that should be promptly recognized and treated. Although invasive imaging modalities, namely fluorescein angiography and indocyanine green angiography, are still the gold standard for the diagnosis and follow-up of the ocular findings in VKH, the role of retinal non-invasive imaging including optical coherence tomography angiography (OCTA) is under investigation and is not mentioned in the current diagnostic criteria of VKH. The aim of this manuscript was to report the clinical course and the multimodal retinal imaging of a VKH case and to discuss the role of OCTA in this condition. Our case supports the evidence that OCTA is able to help determine disease activity and progression in VKH. We therefore contend that OCTA should be considered for future developing diagnostic criteria of this condition.

Abstract Image

Abstract Image

光学相干断层血管造影在Vogt-Koyanagi-Harada病中的作用。
Vogt-Koyanagi-Harada病(VKH)是一种自身免疫性严重多系统疾病,以眼部和全身病变为特征,应及时识别和治疗。虽然侵入性成像方式,即荧光素血管造影和吲哚菁绿血管造影,仍然是诊断和随访VKH眼部表现的金标准,但包括光学相干断层扫描血管造影(OCTA)在内的视网膜非侵入性成像的作用仍在研究中,目前的VKH诊断标准中未提及。本文的目的是报告一个VKH病例的临床过程和多模态视网膜成像,并讨论OCTA在这种情况下的作用。我们的病例支持OCTA能够帮助确定VKH的疾病活动和进展的证据。因此,我们认为OCTA应该被考虑作为未来发展的诊断标准。
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