Fabio Moreira , Mario Pedrazzoli , Fernando Morgadinho dos Santos Coelho , Marcia Pradella-Hallinan , Maria Cecília Lopes da Conceição , Alberto Jorge Pereira Peregrino , Emílio Carlos de Oliveira , Sergio Tufik
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引用次数: 6
Abstract
Narcolepsy is a chronic sleep disorder. It is linked to the HLA-DQB1*0602 allele. A recent report established a genetic linkage between narcolepsy and the chromosomal region 4p13–q21 that contains the Clock gene. We studied two SNPs in the Clock gene aiming to find any association with narcolepsy. We did not find differences in genetic frequencies in the patients group. We concluded that these two SNPs are not associated with narcolepsy.
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