Synthesis of new triazolopyrimidines and substituted pyrimidines.

Bollettino chimico farmaceutico Pub Date : 2004-09-01
N H Ouf
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Abstract

Hydrazinopyrimidine 3 was prepared and transformed into 4, 5 by the reaction with Ar-Cl and POCl3, respectively. Also 3 transformed into 6, 7 by the reaction with ArCHO and FeCl3 respectively. Compound 8 was prepared and transformed into 9, 10, 11 by the reaction with DDC, ethyl bromoacetate and Sodium ethoxide respectively.

新三唑嘧啶及取代嘧啶的合成。
以Ar-Cl和POCl3为原料制备了肼嘧啶3,并分别转化为4、5。3也分别与ArCHO和FeCl3反应转化为6,7。化合物8分别与DDC、溴乙酸乙酯和乙氧化钠反应转化为化合物9、10、11。
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