[Non-metastatic intrahepatic cholestasis associated with bronchial adenocarcinoma].

Annales de medecine interne Pub Date : 2003-05-01
Pierre Saintigny, Jean-Philippe Spano, Françoise Tcherakian, Marie-Christine Pailler, Jean-Luc Breau
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Abstract

In 1961, Stauffer first described a syndrome characterized by nonmetastatic intrahepatic cholestasis associated with undifferentiated renal adenocarcinoma. Since that time, this syndrome has been associated with other tumor diseases. We describe here a patient with lung adenocarcinoma which led to paraneoplastic cholestasis. We discuss the diagnosis and review the literature, emphasizing the pathophysiology of Stauffer's syndrome.

[与支气管腺癌相关的非转移性肝内胆汁淤积]。
1961年,Stauffer首次描述了一种以未分化肾腺癌相关的非转移性肝内胆汁淤积为特征的综合征。从那时起,这种综合征与其他肿瘤疾病有关。我们在此报告一例肺腺癌导致副瘤性胆汁淤积症的病例。我们讨论了斯托弗综合征的诊断和文献复习,强调病理生理学。
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