Merging the old skeletal biology with the new. II. Molecular aspects of bone formation and bone growth.

Abstract

Molecular aspects of bone formation and bone growth are discussed together with selected genetic disorders of the involved genes. Topics covered include: collagenopathies and osteogenesis imperfecta; core binding factor transcription factors and cleidocranial dysplasia; bone morphogenetic proteins and fibrodysplasia ossificans progressiva; transforming growth factor beta, suture closure, and craniosynostosis; Indian hedgehog, parathyroid hormone-related protein together with its receptor, and Jansen metaphyseal chondrodysplasia.