[Fibronectin mRNA expression in hypertrophic scars].

Abstract

Objective: This study was to compare the content of fibronectin messenger RNA in the normal skin and hypertrophic scars.

Methods: The mRNA levels of fibronectin were measured by quantitative RT-PCR.

Result: The study revealed that in vivo, the content of fibronectin messenger RNA was higher in hypertrophic scars than in normal skin.

Conclusion: It indicates that altered regulation of extracellular matrix components is an important factor for abnormal human wound healing.