A spectrophotometric assay of folic acid concentrations in rats: correlations with age and organ.

V Atanasiu, I Niculescu, O Niculescu, S Iacoban, E Trutia
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Abstract

Spectrophotometric assays have been used to determine FA concentration in tissue homogenates from various organs (liver, kidneys, brain, spleen) in white rats; these studies were undertaken to test the age--and organ--dependent variations of FA concentrations in tissue homogenates. The results showed a marked decrease of FA concentration in the adult group of rats when related to the young group, and in the aged group when compared to the adults respectively. Analysing the determined values of folates in tissue homogenates of various organs (in rats belonging to the same group of age), the highest concentration has been found in the liver homogenate, followed in decreasing order by kidneys and to a much greater distance, by the brain and spleen.

大鼠叶酸浓度的分光光度测定:与年龄和器官的相关性。
用分光光度法测定了大鼠各器官(肝、肾、脑、脾)组织匀浆中的FA浓度;这些研究是为了测试组织匀浆中FA浓度的年龄和器官依赖性变化。结果显示,成年组大鼠FA浓度与幼龄组相比显著降低,老年组大鼠FA浓度与成年大鼠相比显著降低。分析不同器官组织匀浆中叶酸的测定值(在属于同一年龄组的大鼠中),发现肝脏匀浆中浓度最高,其次是肾脏,其次是大脑和脾脏,距离远得多。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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