A survey of four years of experience with intracytoplasmic sperm injection.

Acta Europaea fertilitatis Pub Date : 1995-01-01
F Ubaldi, Z Nagy, J Liu, H Tournaye, M Camus, J Smitz, I Liebaers, P Devroey, A Van Steirteghem
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Abstract

The present report covers the results of a 38-month period in which 2853 consecutive intracytoplasmic sperm injection (ICSI) cycles were performed in 1953 couples. These couples were afflicted with male factor infertility and had at least one previous failed conventional in vitro fertilization (IVF) treatment cycle. In other couples, the husband had semen parameters incompatible with conventional IVF or suffered from excretory or secretory azoospermia where it was possible to recover spermatozoa by microsurgical epididymal sperm aspiration (mesa) or by testicular sperm extraction (tese) procedure. Overall, the 2-PN fertilization rate was 62% per retrieved metaphase II oocyte and 70% per successfully injected metaphase II oocyte. Embryo transfer was performed in 91% of started cycles. The cumulative pregnancy rate (positive HCG) was 34% per started ICSI treatment and 37% per embryo transfer.

胞浆内单精子注射四年经验的调查。
本报告涵盖了对1953对夫妇进行2853个连续胞浆内单精子注射(ICSI)周期的38个月期间的结果。这些夫妇都患有男性因素导致的不育症,并且至少有一次常规体外受精(IVF)治疗失败。在其他夫妇中,丈夫的精液参数与常规试管受精不相容,或患有排泄性或分泌性无精子症,可以通过显微手术附睾精子抽吸(mesa)或睾丸精子提取(tese)手术恢复精子。总的来说,每个回收的中期II卵母细胞的2-PN受精率为62%,每个成功注射的中期II卵母细胞的2-PN受精率为70%。胚胎移植在91%的开始周期中进行。每次开始ICSI治疗的累积妊娠率(HCG阳性)为34%,每次胚胎移植的累积妊娠率为37%。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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