[The modification of the radiation damage to the chromosomes in the somatic cells of radiosensitive Drosophila mutants. The radioprotective action of cysteamine].

Radiobiologiia Pub Date : 1993-01-01
V V Levina, O V Malinovskiĭ
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引用次数: 0

Abstract

The radioprotective effect of cysteamine has been studied in larva nerve ganglia of the radiosensitive mutant rad(20)201G1, mutagen-sensitive mutant mus(2)201G1 and the control strain of drosophila. Cysteamine was shown to produce a radioprotective effect in somatic cells of mus(2)201G1 and the control strain of drosophila which was manifested by the decreased incidence of cells with chromosome aberrations and diminished yield of deletions and exchanges. No significant radioprotective effect of cysteamine was observed in somatic cells of rad(2)201G1 mutant.

辐射敏感果蝇体细胞染色体辐射损伤的修饰。半胱胺的辐射防护作用]。
研究了半胱胺对辐射敏感突变体rad(20)201G1、诱变剂敏感突变体mus(2)201G1和果蝇对照品系幼虫神经节的辐射防护作用。半胱胺在果蝇mus(2)201G1和对照株的体细胞中显示出辐射防护作用,表现为染色体畸变细胞的发生率降低,缺失和交换的数量减少。半胱胺对rad(2)201G1突变体的体细胞无明显的辐射防护作用。
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