[The effect of whole-body gamma irradiation on 5'-nucleotidase activity in the blood plasma of rats].

Abstract

Alteration dynamics of 5'-nucleotidase (EC 3.1.3.5) in rat plasma was studied after whole-body gamma-irradiation. External gamma-irradiation with doses ranging from 0.5 to 11 Gy induced a transient rise of 5'-nucleotidase activity. An increase in the enzyme activity was found to be a function of dosage and post-exposure time. The moment of enzyme activity rise vs dose was represented as an exponential curve. The rise in plasma 5'-nucleotidase activity was assumed to be the result of lesions in flexible tissue (type F).