Purified FSH as a treatment for a cervical hostility.

Acta Europaea fertilitatis Pub Date : 1993-01-01
M Nicotra, C Muttinelli, G Rolfi, P Amato
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Abstract

Abnormal cervical mucus (CM) quality and quantity is considered one of the causes of infertility which occurs in only 2 to 8 per cent of infertile couples. The periovulatory mucus with its specific properties is necessary to determine a correct Post Coital Test (PCT). Twenty patients, with infertility for over 18 months and with a baseline negative PCT (repeated at least three times) for abnormal CM, were treated with pFSH. Our results show that the pFSH improves the quality and quantity of CM in all for our patients including an improvement of penetration and motility spermatozoa in 55 per cent of our cases. Therefore we suggest the routine pFSH use in case of cervical hostility and recurrent negative PCT.

纯化卵泡刺激素治疗宫颈敌意。
宫颈粘液(CM)的质量和数量异常被认为是不孕症的原因之一,只有2%至8%的不育夫妇发生这种情况。具有特定性质的排卵周粘液是确定正确的性交后试验(PCT)所必需的。20例不孕超过18个月且PCT基线阴性(至少重复3次)的异常CM患者接受pFSH治疗。我们的结果表明,pFSH改善了我们所有患者CM的质量和数量,包括在55%的病例中改善了精子的穿透性和运动性。因此,我们建议在宫颈敌意和PCT反复阴性的情况下常规使用pFSH。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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