Correlation between postswim-up hypoosmotic swelling test and in vitro fertilization results.

Abstract

Objective: To determine correlation between hypoosmotic swelling (HOS) test on post-swim-up sperm and results of IVF.

Setting: University clinic IVF program.

Patients and interventions: Sixty-three women, with various infertility factors; Buserelin plus hMG and hCG used for all patients. HOS test performed on original and swim-up samples of husband's semen.

Outcome measures: Fertilization, as shown by two pronuclei and two polar bodies 18 hours post-insemination.

Results: Post-swim-up HOS test had a correlation (r) of .68 (P < .001) with fertilization.