Orosomucoid and haptoglobin polymorphisms in two Spanish Pyrenean populations.

Abstract

Serum samples of autochthonous individuals from the Garrotxa prepyrenean region, and the Pallars Sobirà valley were screened for HP (Haptoglobin) and ORM (Orosomucoid) types by polyacrylamide isoelectric focusing and electrophoresis. The allele frequencies estimated were HP*1 = 0.3902 and ORM1*S = 0.3697 for Pallars Sobirà, and HP*1 = 0.4161 and ORMS1*S = 0.3691 in the Garrotxa. While our results for the HP system are within the range of variation of the Iberian Peninsula, the ORM1 protein shows a remarkable degree of variation among these populations.