{"title":"Pleurotus Fruiting Bodies Contain the Inhibitor of 3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase—Lovastatin","authors":"Nina Gunde-Cimerman, Aleksa Cimerman","doi":"10.1006/emyc.1995.1001","DOIUrl":null,"url":null,"abstract":"<div><p>Gunde-Cimerman, N., and Cimerman, A. 1995. <em>Pleurotus</em> fruiting bodies contain the inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase-lovastatin. <em>Experimental Mycology</em> 19, 1-6. In the fruiting bodies of the fungus <em>Pleurotus ostreatus</em>, also called the oyster mushroom, we found a competitive inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase—lovastatin. The appearance of the inhibitor during the development of fruiting bodies was followed and lovastatin determined in the vegetative mycelium, in the primordia, as well as in different parts of sporocarps of different sizes. Less lovastatin was found in stipes as compared to pili or in mature stages in the lamellae and basidiospores.</p></div>","PeriodicalId":12110,"journal":{"name":"Experimental Mycology","volume":"19 1","pages":"Pages 1-6"},"PeriodicalIF":0.0000,"publicationDate":"1995-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1006/emyc.1995.1001","citationCount":"130","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Experimental Mycology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0147597585710018","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 130
Abstract
Gunde-Cimerman, N., and Cimerman, A. 1995. Pleurotus fruiting bodies contain the inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase-lovastatin. Experimental Mycology 19, 1-6. In the fruiting bodies of the fungus Pleurotus ostreatus, also called the oyster mushroom, we found a competitive inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase—lovastatin. The appearance of the inhibitor during the development of fruiting bodies was followed and lovastatin determined in the vegetative mycelium, in the primordia, as well as in different parts of sporocarps of different sizes. Less lovastatin was found in stipes as compared to pili or in mature stages in the lamellae and basidiospores.
Gunde-Cimerman, N.和Cimerman, A. 1995。侧耳子实体含有3-羟基-3-甲基戊二酰辅酶A还原酶-洛伐他汀抑制剂。实验真菌学19,1-6。在平菇(Pleurotus ostreatus)的子实体中，我们发现了一种3-羟基-3-甲基戊二酰辅酶a还原酶-洛伐他汀的竞争性抑制剂。研究了该抑制剂在子实体发育过程中的表现，并测定了其在营养菌丝体、原基以及不同大小孢子实不同部位的含量。在茎中发现的洛伐他汀比在毛中或在成熟阶段的片层和担子孢子中发现的要少。
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