{"title":"[Complement level in serum from patients with chronic hepatitis].","authors":"J Milosavljević, M Cvorić-Guzina, M Bozić","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>In persons with chronic active hepatitis (35) and chronic persistent hepatitis (23) the CH 50 values, Clq, Cls, C4, C3, C5, and C9 as well as Cl Inh and C3A levels have been determined. The concentration changes of complement (C) were not conditioned by the existence in serum HBs. The degree of changes in values of C in all patients is in determinate relation with the levels of bilirubin, transaminases and immunoglobulins (G, M, A). The degree of determinate changes of C depends on the severity of clinical picture. The degree of Cl Inh elevation is in correlation with intensity of complement activation. The noticed dissociated values of subcomplements Clq and Cls suggest the presence of immune complexes which could influence the HBsAg detection.</p>","PeriodicalId":75595,"journal":{"name":"Bilten za hematologiju i transfuziju","volume":"9 1-3","pages":"113-9"},"PeriodicalIF":0.0000,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bilten za hematologiju i transfuziju","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
In persons with chronic active hepatitis (35) and chronic persistent hepatitis (23) the CH 50 values, Clq, Cls, C4, C3, C5, and C9 as well as Cl Inh and C3A levels have been determined. The concentration changes of complement (C) were not conditioned by the existence in serum HBs. The degree of changes in values of C in all patients is in determinate relation with the levels of bilirubin, transaminases and immunoglobulins (G, M, A). The degree of determinate changes of C depends on the severity of clinical picture. The degree of Cl Inh elevation is in correlation with intensity of complement activation. The noticed dissociated values of subcomplements Clq and Cls suggest the presence of immune complexes which could influence the HBsAg detection.
在慢性活动性肝炎(35例)和慢性持续性肝炎(23例)患者中，ch50值、Clq、Cls、C4、C3、C5和C9以及Cl Inh和C3A水平已被确定。补体(C)的浓度变化不受HBs存在的限制。所有患者C值的变化程度与胆红素、转氨酶和免疫球蛋白水平有确定关系(G, M, A)。C值变化的确定程度取决于临床症状的严重程度。Cl Inh升高的程度与补体活化的强度有关。注意到亚补体Clq和Cls的解离值提示存在影响HBsAg检测的免疫复合物。
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