Chronic effects of PGBx, a polymeric prostaglandin, on blood leukocyte counts.

Physiological chemistry and physics Pub Date : 1982-01-01
E Polis, F W Cope
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Abstract

PGBx, a polymeric prostaglandin, in chronic doses therapeutic for hereditary diabetes and hereditary obesity in mice, produces significant increases of blood neutrophils and lymphocytes in normal mice, hereditary diabetic mice, and hereditary obese mice. For lymphocytes, but not for neutrophils, the direction of the PGBx effect reverses at doses above 10 micrograms/g of body weight.

聚合前列腺素PGBx对血液白细胞计数的慢性影响。
PGBx是一种聚合前列腺素,慢性剂量治疗遗传性糖尿病和遗传性肥胖小鼠,在正常小鼠、遗传性糖尿病小鼠和遗传性肥胖小鼠中产生显著增加的血液中性粒细胞和淋巴细胞。对于淋巴细胞,而不是中性粒细胞,当剂量超过10微克/克体重时,PGBx的作用方向相反。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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