{"title":"Interaction of vitamin A deficiency and excess fluoride in calcification of rat bones and teeth.","authors":"S S Harris, J M Navia","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Using a 2 X 2 factorial design, we evaluated the possible interaction of vitamin A deficiency and excess fluoride in rat dentin and bone. Simultaneous presence of excess fluoride plus vitamin A deficiency resulted in a significant decrease in bone fluoride concentration compared to the presence of excess fluoride alone. Vitamin A deficiency alone significantly reduced calcium concentration in dentin formed during the deficient period.</p>","PeriodicalId":75427,"journal":{"name":"Acta vitaminologica et enzymologica","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta vitaminologica et enzymologica","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Using a 2 X 2 factorial design, we evaluated the possible interaction of vitamin A deficiency and excess fluoride in rat dentin and bone. Simultaneous presence of excess fluoride plus vitamin A deficiency resulted in a significant decrease in bone fluoride concentration compared to the presence of excess fluoride alone. Vitamin A deficiency alone significantly reduced calcium concentration in dentin formed during the deficient period.