A practical computer-based approach to the analysis of radioligand binding experiments

Abstract

EBDA is a computer program designed to process raw data (dpm) obtained from radioligand binding experiments into a form suitable for use by a non-linear curve fitting program. Processing of the data is facilitated by graphical representation in the form of Scatchard and Hill plots for saturation data, and competition curves and Hofstee plots for drug displacement studies. Preliminary estimates of binding constants required by a non-linear curve fitting program can also be obtained.