{"title":"Effect of haloperidol on monoamines in brain and heart","authors":"Bengt Falck, Lars Nordgren, Evald Rosengren","doi":"10.1016/0028-3908(69)90080-X","DOIUrl":null,"url":null,"abstract":"<div><p>Rats receiving haloperidol for three days showed a dose dependent decrease of brain catecholamines. The hypothermic effect of the drug did not cause this. Haloperidol counter-acts the monoamine depletion of reserpine in both the brain and the heart provided it is given shortly before reserpine.</p></div>","PeriodicalId":14111,"journal":{"name":"International journal of neuropharmacology","volume":"8 6","pages":"Pages 631-634"},"PeriodicalIF":0.0000,"publicationDate":"1969-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0028-3908(69)90080-X","citationCount":"9","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International journal of neuropharmacology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/002839086990080X","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 9
Abstract
Rats receiving haloperidol for three days showed a dose dependent decrease of brain catecholamines. The hypothermic effect of the drug did not cause this. Haloperidol counter-acts the monoamine depletion of reserpine in both the brain and the heart provided it is given shortly before reserpine.
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