Biological considerations for treating alternate fields versus all fields daily with high and low LET radiation.

Strahlentherapie Pub Date : 1985-12-01
R A Gahbauer, J Horton, F Q Ngo, W Roberts, J Blue
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Abstract

The rationale for treating all fields every day with photons was reviewed. Since the effects of neutron radiation are much less dependent on alterations of fractionation schedules, and since preferential sparing for late effects is not obtained by fractionation of neutron dose, less convincing reasons exist for treating all fields every day with neutrons. Treating one field/day would not alter the physical dose distribution or overall treatment time, yet still maintain biological homogeneity. Preliminary in vitro experiments support this conclusion.

每天用高、低LET辐射处理交替田与所有田的生物学考虑。
回顾了每天用光子处理所有场的基本原理。由于中子辐射的效应不太依赖于分选时间表的改变,而且由于对后期效应的优先保留不能通过分选中子剂量获得,因此每天用中子处理所有场的理由就不那么令人信服了。每天治疗一场不会改变物理剂量分布或总治疗时间,但仍保持生物均匀性。初步的体外实验支持这一结论。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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