[Acute-phase markers in gynecologic tumors].

Strahlentherapie Pub Date : 1985-08-01
G Tatra
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Abstract

The serum concentration of 3 acute phase reactants (APR) (Caeruloplasmin, Alpha-1-antitrypsin and C-reactive protein) was measured by Mancini-technique praetherapeutically in a group of 214 patients with different sites of gynecological tumors. A group of 27 healthy women was used for comparison. In benign tumors Caeruloplasmin had in cases of myoma significantly (5%-standard) more elevated levels than normal group. In all cases with malignancies all 3 APR had significantly more elevated levels than in benign tumors. In cases of carcinoma of ovary all 3 APR had significant more elevated levels than benign ovarian tumors. The percentage of praetherapeutically elevated Alpha-1-antitrypsin levels was higher, while the percentage of elevated CRP-levels in cases with benign ovarian tumors ("false positive") was lower in comparison to accepted markers for ovarian cancer. Thus it appears to be indicated to prove the value of measurement of APR for monitoring in gynecological oncology.

[妇科肿瘤急性期标志物]。
采用mancini技术对214例不同部位妇科肿瘤患者的血清3种急性期反应物(APR)(紫蛋白、α -1-抗胰蛋白酶和c反应蛋白)进行治疗前测定。一组27名健康女性被用于比较。在良性肿瘤中,肌瘤患者的蓝蛋白水平明显高于正常组(5%-标准)。在所有恶性肿瘤病例中,所有3种APR水平均明显高于良性肿瘤。在卵巢肿瘤中,3种APR均明显高于良性卵巢肿瘤。治疗前α -1-抗胰蛋白酶水平升高的百分比较高,而良性卵巢肿瘤(“假阳性”)患者crp水平升高的百分比低于卵巢癌的公认标志物。由此可见,APR测量在妇科肿瘤监测中的应用价值。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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