Effect of Preoperative Ibuprofen on Pain Perception and Pulse Rate in Paediatric Patients with Deep Caries: A Randomised Controlled Trial.

IF 2.2 2区医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE

European journal of paediatric dentistry Pub Date : 2026-04-01 DOI:10.23804/ejpd.2026.2598

M Bilmez Selen, B Kuru

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引用次数: 0

Abstract

Aim: To evaluate the effect of preoperative ibuprofen on intraoperative pain and stress responses during vital pulp therapy (VPT), a minimally invasive treatment aimed at preserving pulp vitality, in children with reversible pulpitis.

Methods: Forty-four children aged 7-13 years with reversible pulpitis in mandibular first permanent molars were randomly assigned to either the intervention group (10 mg/kg ibuprofen 40 minutes before treatment, n = 22) or the control group (no premedication, n = 22). Pain was assessed intraoperatively using the Visual Analogue Scale (VAS) and pulse rate monitoring. Postoperative VAS scores were recorded on days 1, 3, and 7. Ethical approval was obtained (Approval No: 2024-KAEK-08; 25.12.2024), and the study was registered at ClinicalTrials.gov (NCT07114198).

Conclusion: Preoperative administration of ibuprofen significantly reduces intraoperative pain and stress responses during VPT in children, improving comfort and cooperation, and may serve as a simple and clinically applicable adjunct in routine paediatric dental practice.

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术前布洛芬对儿童深部龋齿患者疼痛感知和脉搏率的影响：一项随机对照试验。

目的：评价术前布洛芬对可逆性牙髓炎患儿手术过程中疼痛和应激反应的影响，VPT是一种旨在保持牙髓活力的微创治疗。方法：将44例7 ~ 13岁的下颌第一恒磨牙可逆性牙髓炎患儿随机分为干预组（治疗前40分钟使用10 mg/kg布洛芬治疗，n = 22）和对照组（未预先使用布洛芬治疗，n = 22）。术中疼痛采用视觉模拟评分（VAS）和脉搏监测进行评估。术后第1、3、7天分别记录VAS评分。该研究已获得伦理批准（批准号：2024-KAEK-08； 25.12.2024），并在ClinicalTrials.gov注册（NCT07114198）。结论：术前应用布洛芬可明显减轻小儿VPT术中疼痛和应激反应，提高患者的舒适感和配合度，可作为一种简便、临床适用的辅助手段应用于儿科常规牙科实践。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

European journal of paediatric dentistry DENTISTRY, ORAL SURGERY & MEDICINE-PEDIATRICS

CiteScore

4.60

自引率

19.40%

发文量

审稿时长

6-12 weeks

期刊介绍： The aim and scope of the European Journal of Paediatric Dentistry is to promote research in all aspects of dentistry related to children, including interceptive orthodontics and studies on children and young adults with special needs.