Feedback Total-Activity Conservation of Boolean Control Networks

IF 4.9 2区工程技术 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC

IEEE Transactions on Circuits and Systems II: Express Briefs Pub Date : 2025-08-27 DOI:10.1109/TCSII.2025.3603414

Wenrong Li;Haitao Li;Lingling Wu

引用次数: 0

Abstract

The law of conservation is crucial to guarantee the robustness of gene expression and signal transduction processes in biological systems. This brief analyzes the feedback total-activity conservation of Boolean control networks (BCNs) based on the semi-tensor product of matrices. First, by constructing the conservative characteristic matrix, a matrix-based criterion is presented to verify the total-activity conservation of BCNs. Secondly, by establishing the control index set, all possible state feedback controllers are designed to achieve the total-activity conservation for BCNs. Finally, an example of lac operon in the Escherichia coli is given to illustrate the proposed results.

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布尔控制网络的反馈全活度守恒

守恒定律对于保证生物系统中基因表达和信号转导过程的稳健性至关重要。本文简要分析了基于矩阵半张量积的布尔控制网络的反馈全活动守恒性。首先，通过构造保守性特征矩阵，提出了一种基于矩阵的准则来验证bcn的总活度守恒性。其次，通过建立控制指标集，设计所有可能的状态反馈控制器，实现bcn的总活动守恒。最后，以大肠杆菌中的lac操纵子为例说明了所提出的结果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

IEEE Transactions on Circuits and Systems II: Express Briefs 工程技术-工程：电子与电气

CiteScore

7.90

自引率

20.50%

发文量

883

审稿时长

3.0 months

期刊介绍： TCAS II publishes brief papers in the field specified by the theory, analysis, design, and practical implementations of circuits, and the application of circuit techniques to systems and to signal processing. Included is the whole spectrum from basic scientific theory to industrial applications. The field of interest covered includes: Circuits: Analog, Digital and Mixed Signal Circuits and Systems Nonlinear Circuits and Systems, Integrated Sensors, MEMS and Systems on Chip, Nanoscale Circuits and Systems, Optoelectronic Circuits and Systems, Power Electronics and Systems Software for Analog-and-Logic Circuits and Systems Control aspects of Circuits and Systems.